Blu-ray Inno released the world's first biovascular 3D printer

On October 25, 2015, in Chengdu, Sichuan, witnessed by hundreds of well-known academicians, experts and scholars in the fields of biomedicine, health care and intelligent manufacturing, Blu-ray Development (stock code: 600466.SH) is a wholly-owned subsidiary. Sichuan Blu-ray Yingnuo Biotechnology Co., Ltd. solemnly announced that it has achieved a major breakthrough in the 3D bio-printing vascular project with complete independent intellectual property rights and the “National High-Tech Research and Development Program (863 Program)”. The world's first 3D biovascular printer was successfully launched. More than a year ago, the 3D bio-printing vascular project, which was developed by Blu-ray Inno, was shortlisted for the National 863 Program. The research period lasted for three years, but Blu-ray Inno was able to achieve major technological breakthroughs in just one and a half years.

At the press conference, we can see that, unlike the existing 3D bio-printers on the market, 3D bio-vascular printers can print out hollow structures unique to blood vessels and multiple layers of different types of cells. This is the world's first. The characteristics of 3D biovascular printers are also demonstrated: the world's first 3D bioprinting space rotating platform, dual-nozzle printing technology for precise and collaborative work, visual interactive printing operating system, printheads and environmental control systems... At the press conference, I got a wonderful presentation, which made the experts and scholars present amazed.

Professor Kang Yujian is talking about Blu-ray Inno's 3D bio-printing technology. “The essential element for constructing any organ is to transport nutrients to the organs. Together with Blu-ray Inno’s 'bio-brick' technology, it relies on the data model of the cloud platform. We have successfully achieved angiogenesis with the help of 3D biovascular printers. This is the basis for building all the artificial organs of artificial organisms. Blu-ray Inno has taken a solid step in the process of organ reconstruction.” The first batch of “Thousand Talents Plan” "Specially Appointed Experts, Academician of the American Academy of Toxicology, Chairman of the International Union for Regenerative Medicine Research Applications and Regulations, Executive Chairman of the 3D Printing Technology Council of China 3D Printing Technology Industry Alliance, and Prof. Kang Yujian, Chief Scientist of Blu-ray Inno, introduced at the press conference. .

The core technology of 3D bioprinting is Biosynsphere. It is a new type of precise stem cell culture system with biomimetic function. It uses a "biological ink" consisting of seed cells (stem cells, differentiated cells, etc.), growth factors and nutrients, and prints out products in layers with other materials. After printing, it is cultivated to form a physiologically functional tissue structure. "3D bio-printing is completely different from industrial 3D printing using raw materials such as titanium alloy, bioceramics, polymer, etc., such as printing dentures, prostheses, even cars, houses, etc. The fundamental difference between the two is the activity. 3D Bioprinting prints products that contain cellular components and are biologically active," said Ren Dongchuan, chairman of Blu-ray Inno.

The Blu-ray development announcement stated that they have invested 215 million yuan in technology research and development and research team building. Blu-ray Inno has also established a partnership mechanism, which will increase the capital of the company by the core personnel of Blu-ray Inno, with a total capital increase of 16.15 million yuan. At the intersection of Xixin Avenue and Dikang Avenue in Gaoxin West District, Chengdu, Sichuan, the “3D Bioprint Global Innovation Center” has been erected, and a larger follow-up investment is underway, the world's first 3D bioprinting innovation industrial park – “ The Blu-ray? Optics Valley main building has been capped and is currently undergoing interior decoration, laboratory renovation and procurement of experimental equipment. At the end of August 2016, it will be completed and put into use.

In the media interview, Yang Lan, chairman of Blu-ray Development, recalled the process of getting to know Kang Yujian. As the largest real estate company in Southwest China, Yang Lan is often invited to participate in some government investment and investment negotiations. At that time, Kang Yujian was introduced as the first batch of “Thousand Talents” national special experts in the Central Organization Department by the Sichuan Provincial Government as a visiting professor of Sichuan Huaxi Hospital. On a common platform, the two had several exchanges. Just as all real estate companies are looking for transformation, Yang Lan is looking for a new investment in the Blue Ocean.

Kang Yujian was also looking for breakthrough opportunities for his research. In 2001, during his time at the University of Louisville, he participated in and helped the school successfully implement the world's first full heart transplant operation. This type of surgery was performed in 14 cases. However, the surgical requirements of up to $250,000 each for adults who need more than 150 pounds of weight can be plagued by cost, application and production processes, and cannot be approved by the US FDA. The emergence of 3D printing technology, let Kang Yujian also want to solve this problem in this way. He shot the artificial heart and achieved the world's first successful 3D printed artificial heart replacement surgery in pigs, but as a biologist, he knows that there are still problems that have not been solved – because they are not biologically active and cannot solve blood vessels. Endothelialization, vascular blockage and other issues. How can we combine the above two problems? As early as 1996-1997, Kang Yujian published two papers on transgenic mice in JBC and JCI, the most authoritative bioscience journals in the United States. It is well known that an embryonic stem cell can differentiate into different organs at different times and eventually become a complete human, but no one can clearly explain why it can produce different differentiation at different times. Kang Yujian launched a study on this. Stem Cell + 3D Printing = The concept of 3D bioprinting was born.

In the future, Blu-ray Inno plans to invest, acquire, introduce and 3D bio-printing, biomedicine, regenerative medicine and other related talents, technologies, laboratories, etc. in the world, precisely because of this "Inno +" concept. At the press conference, Blu-ray Inno has signed a contract with the University of Dundee. The founder of the world's minimally invasive surgery, Sir Alfred Cuschieri of the University of Dundee, UK, said that he will cooperate with Blu-ray Inno in the field of 3D bio-printing. They also plan to set up branches in New York, Hong Kong, and Singapore. Under the "Technology + Capital" cooperation model, another "Ten Thousand Talents Program" national special experts, has been employed by the University of Leeds and the National University of Singapore, the British Institute of Mechanical Engineers senior researcher Zhou Huixing joined the Blu-ray Inno, the main research 3D Bioprinter development.

There is also a special link at the press conference. Due to the strong confidence in the 3D bio-printing market and the development prospects of Blu-ray Inno, the founder of Quantum Fund and world-famous investor Rogers made a special trip to Chengdu to visit and research Blu-ray Inno 3D bio-printing. project.

(Editor)

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